There are 3 topic domains: a) Scope and Purpose, b) Stakeholder Involvement, and

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There are 3 topic domains: a) Scope and Purpose, b) Stakeholder Involvement, and c) Rigour of Development. I’m including the notes I started with and refer to the clinical practice guideline for more detail.
1. DOMAIN 1: The overall objective(s) of the guideline is (are) specifically described. 2. The health question(s) covered by the guideline is (are) specifically described. 3. The population (patients, public, etc.) to whom the guideline is meant to apply is specifically described.
Item content includes the following CRITERIA: A)• health intent(s) (i.e., prevention, screening, diagnosis, treatment, etc.) • expected benefit or outcome • target(s) (e.g., patient population, society) Additional CONSIDERATIONS: • Is the item well written? Are the descriptions clear and concise? • Is the item content easy to find in the guideline? tem content includes the following CRITERIA: B) • target population • intervention(s) or exposure(s) • comparisons (if appropriate) • outcome(s) • health care setting or context C) target population, gender and age • clinical condition (if relevant) • severity/stage of disease (if relevant) • comorbidities (if relevant) • excluded populations (if relevant)
2. DOMAIN 2: 4.The guideline development group includes individuals from all relevant professional groups. 5. The views and preferences of the target population (patients, public, etc.) have been sought. 6. The target users of the guideline are clearly defined. 4) • For each member of the guideline development group, the following information is included: ! name ! discipline/content expertise (e.g., neurosurgeon, methodologist) ! institution (e.g., St. Peter’s hospital) ! geographical location (e.g., Seattle, WA) ! a description of the member’s role in the guideline development group 5) statement of type of strategy used to capture patients’/public’s’ views and preferences (e.g., participation in the guideline development group, literature review of values and preferences) • methods by which preferences and views were sought (e.g., evidence from literature, surveys, focus groups) • outcomes/information gathered on patient/public information • description of how the information gathered was used to inform the guideline development process and/or formation of the recommendations 6) • clear description of intended guideline audience (e.g. specialists, family physicians, patients, clinical or institutional leaders/administrators) • description of how the guideline may be used by its target audience (e.g., to inform clinical decisions, to inform policy, to inform standards of care)
Rigor of development: 7. Systematic methods were used to search for evidence. 8. The criteria for selecting the evidence are clearly described. 9. The strengths and limitations of the body of evidence are clearly described. 10. The methods for formulating the recommendations are clearly described. 11. The health benefits, side effects, and risks have been considered in formulating the recommendations. 12. There is an explicit link between the recommendations and the supporting evidence. 13. The guideline has been externally reviewed by experts prior to its publication. 14. A procedure for updating the guideline is provided. 7) named electronic database(s) or evidence source(s) where the search was performed (e.g., MEDLINE, EMBASE, PsychINFO, CINAHL) • time periods searched (e.g., January 1, 2004 to March 31, 2008) • search terms used (e.g., text words, indexing terms, subheadings) • full search strategy included (e.g., possibly located in appendix 8) description of the inclusion criteria, including ! target population (patient, public, etc.) characteristics ! study design ! comparisons (if relevant) ! outcomes ! language (if relevant) ! context (if relevant 9) descriptions of how the body of evidence was evaluated for bias and how it was interpreted by members of the guideline development group • aspects upon which to frame descriptions include: ! study design(s) included in body of evidence ! study methodology limitations (sampling, blinding, allocation concealment, analytical methods) ! appropriateness/relevance of primary and secondary outcomes considered ! consistency of results across studies ! direction of results across studies ! magnitude of benefit versus magnitude of harm ! applicability to practice contex 10) tem content includes the following CRITERIA: • description of the recommendation development process (e.g., steps used in modified Delphi technique, voting procedures that were considered) • outcomes of the recommendation development process (e.g., extent to which consensus was reached using modified Delphi technique, outcome of voting procedures) • description of how the process influenced the recommendations (e.g., results of Delphi technique influence final recommendation, alignment with recommendations and the final vote) 11) • supporting data and report of benefits • supporting data and report of harms/side effects/risks • reporting of the balance/trade-off between benefits and harms/side effects/risks • recommendations reflect considerations of both benefits and harms/side effects/risks 12) the guideline describes how the guideline development group linked and used the evidence to inform recommendations • each recommendation is linked to a key evidence description/paragraph and/or reference list • recommendations linked to evidence summaries, evidence tables in the results section of the guideline 13) purpose and intent of the external review (e.g., to improve quality, gather feedback on publish recommendations, assess applicability and feasibility, disseminate evidence) • methods taken to undertake the external review (e.g., rating scale, open-ended questions) • description of the external reviewers (e.g., number, type of reviewers, affiliations) • outcomes/information gathered from the external review (e.g., summary of key findings) • description of how the information gathered was used to inform the guideline development process and/or formation of the recommendations (e.g., guideline panel considered results of review in forming final recommendations) 14) Item content includes the following CRITERIA: • a statement that the guideline will be updated • explicit time interval or explicit criteria to guide decisions about when an update will occur • methodology for the updating procedure is reported
Only address the 3 domains specified from the Agree II tool.

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